From Klamath to the Klamin® extract

General neuro-modulating effect: significant mood enhancing, attention promoting, and neuro-regenerating properties.
Thanks to the moderate amount of phenylethylamine (PEA) that it contains,

Klamath RW®max is able to carry out positive physiological effects on our ‘smaller’ problems such as mood fluctuations and memory and attention disturbances.

However, the concentration of PEA that is required in order to obtain significant neurological effects is greater than that present in the microalga, and needs moreover the support of molecules that act as natural MAO-B inhibitors.

The Center for Nutraceutical Research directed by dr. Scoglio, in collaboration with various university researchers, have discovered that Klamath algae contains precisely these molecules and has patented a specific extract, Klamin®, which concentrates a greater and more sufficient quantity both of the PEA and MAO-B inhibitors naturally present in Klamath algae.

Phenylethylamine is an endogenous amine that has been defined, not coincidentally, as the “molecule of love”, since this is what our body produces in abundance when we were are in love with another person or even life itself! Now taking phenylethylamine (PEA) by itself would barely have any effect, since once ingested PEA is rapidly destroyed by the specific MAO-B enzymes in our body. In Klamath algae, however, there are different molecules, from the same aforementioned AFA-phycocyanins, to algal microsporins (MAAs) to another important molecule typical of Klamath algae (similar to the phytochromes found in plants), which we will fittingly call AFA-phytochrome, and which have shown to be powerful selective inhibitors precisely of those enzymes which destroy PEA; they therefore are able to protect PEA, allowing it to carry out its effects on the neurocerebral system.

The most important fact is that these molecules, although they are the most powerful inhibitors of MAO-B among all natural molecules, carry out a physiological action that produces absolutely no side effects, because, unlike the specific pharmaceutical drugs, they only temporarily inhibit MAO-B enzymes, without destroying them (and is this destructive action which generates side effects).
PEA is a general neuromodulator because it is able to activate or even alternatively inhibit various neurotransmitters such as dopamine and, in certain conditions, serotonin. This allows it to carry out a revitalizing and balancing action on the nervous system, alleviating depression and, if necessary, also anxiety; it also promotes energy through its activation of adrenalin, but also by favouring sleep and restfulness through its activation of serotonin and the hypotalamic-pituitary axis.This synergy between PEA and natural MAO-B inhibitors also carries out another fundamental function, that of protecting us against the onset of ageing, because as we get older the amount of dopamine in our body decreases (- 13% every ten years after the age of forty), while there is a parallel increase in MAO-B enzymes (+ 250% over the age of fifty) which are the main factors fueling our ageing process!

In one of these studies, conducted on women in menopause, other further systemic effects were revealed, linked to the decrease in dopaminergic transmission, with improvements being produced also in conditions such as, a decreased libido and memory loss.